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Alpha GPC Manufacturer | CAS 28319-77-9 | StableGPC™ Solution

  1. Product Name: Alpha GPC Powder (L-Alpha Glycerylphosphorylcholine) | Industrial Bulk Supply

  2. Assay (HPLC): ≥99.0% (Certified L-Alpha Isomer Integrity)

  3. Appearance: White to off-white crystalline powder (Uniform Particle Size)

  4. CAS No.: 28319-77-9

  5. Solubility: Highly Water-Soluble (Clear & Colorless Solution)

  6. Stability: Optimal between pH 4.5 – 7.0 (StableGPC™ Moisture-Shielded)

  7. Lead Time: 3–7 Working Days (Global Bulk Stock)

  8. Packaging: 25kg Standard Drum / 1kg Sample Available

  9. Compliance: GMP Certified / Full Batch COA & TDS Provided

  10. Application: Nootropic Formulations / Cognitive Health APIs / Pre-Workout Supplements / OEM & ODM

BULK SUPPLY & TECHNICAL ADVISORY
🛡️GMP Certified
🔬HPLC Tested
🌍Global Logistics
📦Free Samples

Stock Status1,500kg Ready-to-Ship
Lead Time3-5 Working Days
Factory DirectGMP / USP / FDA

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29-YEAR EXPERTISE

Alpha GPC Powder Bulk Manufacturer

As a premier alpha gpc supplier, Exbiol® (Zhonghong Group) provides high-stability bulk alpha gpc powder. We solve the industry’s moisture-sensitivity paradox through StableGPC™ molecular engineering.

Sourcing Logic
Direct Factory | Flexible MOQ
Global Logistics
3-5 Day Air / DDP Options

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R&D Technical Summary

  • 99.83% Assay: Verified by Potentiometric Titration.
  • -2.743° Rotation: Certified L-Alpha Isomer purity.
  • Residual Solvent: Methanol < 100ppm (USP 467).
  • Stability: Verified under 40°C/75% RH protocols.

R&D Note: Our StableGPC™ technology uses Acacia matrices to increase Glass Transition Temp (Tg), preventing browning in RTD beverages.

1. What is Alpha GPC Powder?

Alpha GPC (L-Alpha Glycerylphosphorylcholine) is a high-potency choline donor and a biosynthetic precursor of acetylcholine. As a global alpha gpc powder bulk manufacturer, we specialize in overcoming the “Hygroscopicity Barrier.” While standard GPC liquefies within 2 hours of exposure, our StableGPC™ grade maintains crystalline integrity, allowing for seamless automated encapsulation and tableting in humid manufacturing environments.

2. Industrial Dashboard Specifications

Assay (Dried)
99.83%
Water Content
0.10%
Specific Rotation
-2.743°
CAS Number
28319-77-9

3. Source & Manufacturing Origin

Our bulk alpha gpc is synthesized from GMO-Free Soy Lecithin via a proprietary catalytic hydrolysis process. All manufacturing occurs in our Shaanxi-based, ISO-certified facility. Unlike low-tier traders, Exbiol controls the entire de-acylation chain, ensuring zero cross-contamination with residual soy proteins, making it safe for allergen-sensitive formulations.

4. Biomolecular Mechanism

Alpha GPC crosses the blood-brain barrier (BBB) more effectively than standard choline salts. It provides a direct substrate for the synthesis of Phosphatidylcholine and Acetylcholine. This dual-pathway mechanism supports both neural signal transduction (cognitive focus) and cell membrane repair (long-term neurological health).

5. Industrial Application Benefits

  • Cognitive Performance: Studied for investigative roles in focus and memory enhancement.
  • Sports Nutrition: Research explores its role in Mind-Muscle connection and explosive power.
  • Stability Engineering: StableGPC™ allows for longer product shelf-life without browning.

6. StableGPC™ Matrix Technology

Grade: 99% Anhydrous

Best for Liquid Formulas (RTDs). Provides 100% clarity. Requires vacuum-handling during manufacturing to prevent liquefaction.

Grade: 50% Granular (DL-BEI)

Best for Capsules & Tablets. Features an Acacia Seyal matrix for 300% higher moisture resistance.

7. Industrial Technology Evolution

The alpha gpc supplier market has evolved from crude solvent extraction to Exbiol’s Generation 4 Multi-Stage Vacuum Crystallization. By controlling the molecular embedding at the point of spray-drying, we’ve increased the Glass Transition Temperature (Tg), making our GPC stable in high-humidity markets where competitors fail.

8. Analytical Specifications (Full COA)

Chemical & Physical Release
Test ItemSpecificationMethod
Assay (Dried)98.0% – 102.0%Potentiometric
Specific Rotation-2.4° ~ -2.85°In-house HPLC
Residual Methanol< 3,000 ppmHeadspace GC
Heavy Metal & Microbiological Control
Test ItemSpecificationMethod
Lead (Pb)< 0.5 ppmICP-MS
Total Plate Count< 1,000 cfu/gUSP <61>

9. Manufacturing Flow

Soy PC Extraction → Catalytic Hydrolysis → De-acylation → Nano-filtration → Molecular Embedding Spray-Drying (RH <15%) → Nitrogen Flush Packaging.

10. Storage & Triple-Seal Logistics

alpha gpc powder bulk is shipped in a Triple-Barrier system: Double-layer anti-static bags + Vacuum-sealed Aluminum foil bag + HDPE drum. Store at <20°C in humidity-shielded warehouses. Once opened, use nitrogen flush to reseal.

11. Sourcing MOQ & Global Delivery

Trial MOQ: 1kg Sample Pack
Wholesale MOQ: 25kg Standard Drum
Lead Time: 3-7 Working Days

12. Clinical Research & Data

Scientific studies investigate Alpha GPC for potential roles in cholinergic support. Our R&D team maintains a library of over 250 clinical abstracts related to GPC’s investigative role in cognitive signal transduction.

Nutraceuticals
Pharma APIs
Functional Beverages

14 & 15. Industrial Scenarios & Case Study

Case Project: US-based Longevity Brand.
Issue: Capsule leakage in Southeast Asia distribution.
Solution: Transition to Exbiol StableGPC™ (DL-BEI grade).
Result: Zero returns in 12 months. Shelf-life extended to 24 months.

16. Supplier Selection Matrix

MetricStandard Commodity SupplierExbiol® Industrial Grade
Hygroscopicity ControlLiquefies in minutesStableGPC™ Molecular Embedding
Solvent Residues< 3,000 ppm (Methanol)< 100 ppm (Ultra-Pure)
Batch IntegrityVariable ChromatogramAgilent HPLC-Batch-Lock Fingerprinting

17. Technical FAQ for Bulk Buyers

Where can I buy Alpha GPC powder in bulk with HPLC verification?

Exbiol is a direct alpha gpc manufacturer. We provide Agilent HPLC-ELSD chromatograms for every batch to ensure 99.8% assay purity and zero significant impurities, facilitating high-end production.

What is the lead time for alpha gpc supplier orders internationally?

We maintain a rolling inventory of 1,500kg. Orders under 500kg typically ship within 3 working days via air freight. Larger sea freight orders range between 15-20 days.

18. References & Regulatory Sources

1. [Analytical] Batch Release Record #P20251201 (Agilent 1290). | 2. [Regulatory] US FDA GRAS Notice (GRN) No. 419. | 3. [Stability] ICH Q1A(R2) Validation Report on StableGPC™ Matrix.

Global Industrial Procurement Center

Partner with Exbiol® to eliminate formulation risks. Manufactured by Shaanxi Zhonghong Investment Technology Co., Ltd.

FACTORY DIRECT
Ready for Dispatch
QC RELEASE
100% Traceable

📧 [email protected] | [email protected]

Official Hub: www.exbiol.com

BULK SUPPLY & TECHNICAL ADVISORY
🛡️GMP Certified
🔬HPLC Tested
🌍Global Logistics
📦Free Samples
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