Anthocyanin Manufacturer | Bulk 25% HPLC Powder | Wholesale Standardized Extract Supply
1. What is Anthocyanin Extract?
Anthocyanins (CAS 11029-12-2) are water-soluble vacuolar pigments belonging to the flavonoid group. In the industrial sector, they are recognized as high-potency antioxidants and natural colorants. Unlike crude berry powders, Exbiol® Anthocyanin is a refined isolate standardized for Anthocyanosides. It is primarily used in nutraceuticals to support vascular integrity and vision health markers, offering a bio-available fraction that crosses the blood-retinal barrier.
2. Technical Specifications
| Parameter | Industrial Standard (HPLC) |
|---|---|
| Active Purity | Anthocyanins ≥ 25.0% HPLC / 36.0% UV-Vis |
| Loss on Drying | ≤ 5.0% |
| Solubility | 100% Water Soluble |
| Solvent Residue | Methanol-Free (Ethanol/Water Only) |
3. Source & Biological Origin
We source authentic Vaccinium myrtillus and Ribes nigrum from high-latitude wild-harvesting zones. These environments trigger maximum anthocyanin production as a plant defense mechanism against UV radiation. Every batch is DNA-verified to ensure zero adulteration with low-cost black rice or mulberry extracts.
4. Mechanism of Action
Anthocyanins function by neutralising reactive oxygen species (ROS) through hydrogen atom transfer. They specifically support the regeneration of rhodopsin in the retina, enhancing night vision markers. Additionally, they modulate the functional property of vascular permeability by inhibiting the breakdown of collagen in basement membranes.
5. Application Benefits
Functional property for accelerating retinal adaptation to dark environments.
May support the reduction of oxidative stress in the vascular endothelium.
6. Usage & Formulation Guide
- Solubility: Fully water-soluble. Add to the aqueous phase at room temperature.
- pH Stability: Sensitive to pH shifts. For vibrant red/purple colors, maintain pH < 4.0. In neutral pH, the powder may shift to blue/grey.
- Thermal Care: Maintain temperatures < 60°C during formulation to prevent pigment degradation.
7. Industrial Evolution
The market has evolved from simple berry juices to Exbiol’s Third-Generation Isomer-verified Isolates. We utilize dual-solvent membrane filtration (Methanol-Free) to isolate 15+ different anthocyanosides, providing a clean-label active that meets the strictest pharmaceutical standards for molecular identity.
8. COA & Quality Control Specifications
8.1 Heavy Metals (ICP-MS Verified)
| Item | Spec | Method |
|---|---|---|
| Lead (Pb) | < 0.5 ppm | ICP-MS |
| Arsenic (As) | < 0.5 ppm | ICP-MS |
8.2 Pesticide Screen (USP <561>)
| Category | Spec | Method |
|---|---|---|
| Multi-Residue | ND | GC-MS/MS |
| Total Pesticides | < 0.01 mg/kg | USP <561> |
8.3 Microbiological Standards
| Analysis | Spec | Method |
|---|---|---|
| Total Plate Count | < 1,000 cfu/g | USP <61> |
| Pathogenic Bacteria | Negative | USP <62> |
9. Manufacturing Flow Description
10. Storage & Packaging
Primary: 1kg Al-foil bag; 25kg standard fiber drum. Store at <20°C in a dry, dark place. Anthocyanins are extremely sensitive to moisture and UV; ensure airtight sealing. Shelf life: 24 months.
11. MOQ, Sample & Global Shipping
MOQ: 1kg for trial orders. Samples: 10g-50g технічних technical samples available with HPLC fingerprinting. Global air dispatch within 3-5 working days from Shaanxi hub.
12. Clinical Data & Scientific Research
In-vitro research indicates that Anthocyanin glycosides significantly upregulate the activity of Nrf2 pathways. Human trials (standardized 25% HPLC) demonstrate a 15% increase in contrast sensitivity markers in participants with high blue-light exposure.
13. Applicable Industries
Functional Beverages
Nutricosmetics
14. B2B Application Scenarios
Ideal for Contract Manufacturers (OEM/ODM) developing anti-oxidation beverage shots, eye-health capsules, and transparent jelly supplements requiring stable natural colorants.
15. Industrial Market Scenarios
For brands targeting the Clean Label Functional Food segment, Anthocyanin provides the “Dual-Function” benefit: a pharmaceutical-grade active ingredient and a natural non-toxic colorant (E163 equivalent).
16. Supplier Comparison & Procurement Guide
Standard Industry Extract
- High Methanol Residues
- Synthetic Dye Adulteration Risk
- Inconsistent Batch Color
Exbiol® Industrial Grade
- Verified Anthocyanosides Fingerprint
- Methanol-Free Solvent System
- 100% Water-Solubility Guaranteed
17. Technical FAQ for Bulk Buyers
Q: How do you verify the fatty acid ratio of your CO2 oil compare to the USP monograph?
Note: Anthocyanin is a water-soluble extract. For our 25% HPLC grade, we verify the **Anthocyanoside Profile** against the USP Bilberry/Blackcurrant standards, ensuring 1:1 biological equivalence to official reference material.
Q: Why is your Anthocyanin 25% off-white or brown instead of bright purple?
High-purity Anthocyanin powder is naturally deep violet to near-black. If it appears brown, it indicates oxidation or high plant tannin residues. Exbiol ensures a dark purple profile through nitrogen-blanketed drying.
Q: Is your material water-soluble?
Yes, Exbiol’s industrial grade is 100% water-soluble. It is specifically filtered to ensure high-clarity in functional beverages without sedimentation.
Q: What is the lead time for 1,000kg?
Standard dispatch is 3-5 working days from our central hub.
Q: Is it non-GMO certified?
Yes, all our berry sources are non-genetically modified and wild-harvested.
18. References & Regulatory Sources
- PubMed: Anthocyanins in visual health and retina.
- FDA: GRAS database for Anthocyanins from fruit sources.
- USP: NF Monographs for Bilberry Extract.
- ISO 16128: Natural Origin Index Verification.
Manufacturer & Quality Assurance
Manufactured by Exbiol® (Shaanxi Zhonghong Investment Technology Co., Ltd.), a GMP-certified specialist in high-purity botanical extracts for pharmaceuticals and functional food.
✔ Batch Traceability & Full Dossiers
✔ Methanol-Free Solvent Control
✔ 15,000kg Bulk Stock Ready
