Ashwagandha Extract Manufacturer | Bulk 5% 10% Withanolides | Wholesale Root-Only Supply
Global Industrial Manufacturing of High-Stability Ashwagandha (Withania somnifera) Solutions.
As the life-science division of Zhonghong Group, Exbiol® leverages 29 years of phytochemical engineering to provide premium Ashwagandha Extract bulk supply. For Sourcing Managers, we resolve production downtime with a 12,000kg ready-stock inventory for 3-day global dispatch. For R&D Specialists, we eliminate the “Withaferin A Toxicity” concern by providing standardized root-only extracts (HPLC 1.5% – 10%) with verified low cytotoxic levels (<1%). Our GMP-certified facility ensures zero batch-to-batch volatility, providing full molecular fingerprinting and audit-ready documentation (MSDS, TDS, COA) for global pharmaceutical and sports nutrition leaders.
1. What is Ashwagandha Extract?
Ashwagandha Extract (Withania somnifera) is a high-potency phytochemical active standardized for its withanolide content. In the industrial sector, it is recognized as the premier adaptogen for cortisol regulation. At Exbiol®, we utilize root-specific extraction to avoid high concentrations of Withaferin A (cytotoxic leaf alkaloid), ensuring a high-purity raw material suitable for long-term clinical and nutricosmetic applications.
2. Technical Specifications Table
| Parameter | Engineering Standard (HPLC/USP) |
|---|---|
| Active Content (HPLC) | Withanolides 1.5% – 10.0% (Standardized) |
| Withaferin A Content | ≤ 1.0% (HPLC Verification of Safety) |
| Mesh Size | 100% Through 80 Mesh |
| Bulk Density | 0.45 – 0.65 g/ml |
3. Source & Origin
Our raw material is sourced from high-quality Withania somnifera root farms. We utilize a “Root-Only” harvest policy, as the aerial parts (leaves) carry a different alkaloid profile that can lead to product instability and toxicity concerns. Every incoming lot undergoes DNA barcoding to verify species authenticity, eliminating adulteration with Withania coagulans.
4. Mechanism of Action
Ashwagandha withanolides function by modulating the Hypothalamic-Pituitary-Adrenal (HPA) axis. At a molecular level, they act as GABAergic ligands and support the cellular functional property of antioxidant enzyme stimulation (SOD, Catalase). This helps modulate cortisol production, supporting overall metabolic and neurological homeostasis during periods of physiological stress.
5. Application Benefits
- Stress Modulation: Functional property for supporting healthy cortisol levels.
- Cognitive Integrity: May support the functional property of acetylcholine preservation.
- Sports Recovery: Functional property for supporting muscle mass maintenance already within a normal range.
6. Usage & Formulation Guide
Solubility Matrix: Partially water-soluble. For functional beverages, use our CWD (Cold Water Dispersible) Grade to prevent sedimentation.
pH Stability: Most stable between pH 4.0 and 7.5. Excessive alkaline environments may cause alkaloid precipitation.
Processing Limit: Maintain processing temperatures below 60°C to preserve the delicate steroidal lactone structure.
7. Industrial Evolution
The industry has evolved from crude ground root to traditional water-extraction, and now to Exbiol’s Green Solvent Low-Temperature Extraction. This third-generation process captures the full spectrum of withanolides without the high-heat degradation common in older methods, ensuring a high-density powder suitable for high-speed automated encapsulation.
8. COA & Quality Control Specifications
Table 8.1: Heavy Metals (ICP-MS)
| Item | Spec | Method |
|---|---|---|
| Lead (Pb) | < 1.0 ppm | ICP-MS |
| Arsenic (As) | < 0.5 ppm | ICP-MS |
| Cadmium (Cd) | < 0.1 ppm | ICP-MS |
Table 8.2: Pesticide Residue Multi-Screen
| Item | Spec | Method |
|---|---|---|
| Organochlorines | Negative | GC-MS/MS |
| Total Pesticides | < 0.01 mg/kg | USP <561> |
Table 8.3: Microbiological Standards
| Item | Spec | Method |
|---|---|---|
| Total Plate Count | < 1,000 cfu/g | USP <61> |
| Salmonella | Negative | USP <62> |
9. Manufacturing Flow Description
Root Selection → Cryogenic Milling → Hydro-alcoholic Extraction → Dual Centrifugation → Vacuum Concentration → Low-Temp Spray Drying → Sifting → Vacuum Sealing.
10. Storage & Packaging
Bulk Supply: 25kg standard fiber drum with double PE inner liner. Store at <25°C, humidity <60%. Hygroscopic powder; ensure airtight seal after opening.
11. MOQ, Sample, Global Shipping
MOQ: 25kg. 10g-50g Tech Samples provided with full batch chromatograms. Global air freight from Shaanxi hub within 3-5 working days.
12. Clinical Data & Scientific Research
Published PubMed clinical trials on standardized 5% Withanolides (300mg – 600mg daily) suggest a functional property in supporting healthy serum cortisol levels. No medical claims are implied.
13. Applicable Industries
Sports Nutrition
Pet Nutrition
14. B2B Application Scenarios
Our bulk extract is optimized for “Stress & Sleep” capsule formulas, post-workout recovery shakes, and nootropic complexes requiring high-purity, standardized alkaloids.
15. Industrial Market Scenarios
In the competitive **Amazon Stress-Support** category, choosing an HPLC-fingerprint verified extract is the primary differentiator for brands seeking Tier-1 retail shelf space and third-party transparency badges.
16. Supplier Comparison & Procurement Guide
| Criterion | Generic Leaf-Spiked Extract | Exbiol® Root-Only Tech |
|---|---|---|
| Safety Profile | High Withaferin A (Cytotoxic risk) | Low Withaferin A (<1%) |
| Standardization | Gravimetric (Inaccurate) | HPLC Fingerprint Verified |
17. Technical FAQ for Bulk Buyers
Q: Why is HPLC standardization superior to Gravimetry for Ashwagandha?
A: Gravimetry measures all plant sterols, often leading to inflated numbers. HPLC specifically isolates withanolides, ensuring every mg contributes to the functional property stated on your label.
Q: Does your extract contain any milk-based solvents?
A: No. We utilize a pure hydro-alcoholic extraction process, making our material 100% Vegan and Allergen-Free.
Q: Can I use your Ashwagandha in liquid gummies?
A: Yes, our CWD grade is designed to disperse instantly in semi-liquid matrices without clumping.
Q: What is the lead time for 1,000kg?
A: Standard dispatch is 3 working days from our Shaanxi hub.
18. References & Regulatory Sources
- PubMed: Withanolides and cortisol regulation meta-analysis.
- FDA NDI Database for Withania somnifera.
- USP Monographs for Botanical Ingredients.
Ashwagandha Extract Manufacturer & QA
Manufactured by Exbiol® (Shaanxi Zhonghong Investment Technology Co., Ltd.), a GMP-certified specialist in high-purity botanical extracts.
✔ Root-Only Verification
✔ 12,000kg Bulk Stock Ready
✔ Zero-Allergen Vegan Process
