Centella Asiatica 95% TECA | CAS 84455-29-8

  1. Product Name: Centella Asiatica Extract (TECA) | Industrial Bulk Supply

  2. Assay (HPLC): ≥95.0% Total Triterpenes (Certified 4-Marker Fingerprint Verified)

  3. Appearance: Off-white to White Crystalline Powder (Uniform Fine Mesh)

  4. CAS No.: 84455-29-8

  5. Solubility: Highly Soluble in Propylene Glycol & Ethanol; CWD Grade available for water.

  6. Stability: Thermo-stable up to 80°C | Optimal efficacy between pH 4.5 – 7.5

  7. Lead Time: 3–7 Working Days (10,000kg+ Bulk Ready-Stock in Shaanxi Hub)

  8. Packaging: 25kg Standard Fiber Drum / 1kg R&D Trial Samples

  9. Compliance: GMP Certified / Full Batch COA, DNA Barcoding Verification & SDS

  10. Application: Professional Dermal Repair / Post-Procedure Care / Anti-aging OEM & ODM

🛡️GMP Certified
🔬HPLC Tested
🌍Global Shipping
📦MOQ: 1kg/25kg

Centella Asiatica Extract Manufacturer | Bulk Gotu Kola Powder | Wholesale TECA 95% Supply

Global Industrial Supply of High-Stability Centella Asiatica (TECA) Solutions.

As the life-science division of Zhonghong Group, Exbiol® leverages 29 years of phytochemical engineering to provide premium Centella Asiatica Extract bulk supply. For Sourcing Managers, we resolve the “Supply Lead-Time Crisis” with a 10,000kg ready-stock inventory for 3-day global dispatch. For R&D Giant-level demands, we offer standardized TECA (Total Extract of Centella Asiatica) containing 95% Triterpenes (Asiaticoside, Madecassoside, Asiatic Acid, Madecassic Acid). Our GMP-certified facility ensures zero batch-to-batch volatility, providing full molecular fingerprinting and audit-ready documentation (MSDS, TDS, COA) for Tier-1 dermaceutical leaders.

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29-Year Factory Audited

1. What is Centella Asiatica Extract?

Centella Asiatica Extract, often termed Gotu Kola or Cica, is a botanical active standardized for its pentacyclic triterpenoid content. In industrial skincare and pharmaceuticals, it is recognized for its “Cica-Repair” functional properties. At Exbiol®, we produce a purified extract that isolates the four key biomarkers: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid, ensuring a high-potency raw material for professional barrier-repair and collagen-support formulations.

2. Technical Specifications Table

Technical Parameter Standard / Specification
Active Content (HPLC) Total Triterpenes ≥ 10.0% – 95.0% (TECA)
Marker Compound Ratio Asiaticoside : Madecassoside (Optimized 40:60)
Solvent Residue Ethanol Only < 5000 ppm (No Methanol)
Loss on Drying ≤ 5.0%

3. Source & Botanical Origin

Our raw material is sourced from high-humidity tropical wetlands in Southeast Asia and processed in our Shaanxi industrial hub. We select only the aerial parts of the Centella asiatica (L.) Urb. to ensure peak triterpene accumulation. Every harvest undergoes DNA barcoding to verify species authenticity, preventing adulteration with common swamp weeds.

4. Mechanism of Action

The molecular mechanism involves the stimulation of TGF-β signaling. Asiaticoside and Madecassoside promote the synthesis of Type I and III collagen within human fibroblasts. Additionally, the acidic components (Asiatic and Madecassic acids) may support the functional property of matrix metalloproteinase (MMP) inhibition, protecting the skin’s extracellular matrix from degradative aging.

5. Application Benefits

  • Skin Repair: May support the functional property of epidermal barrier restoration.
  • Soothing: Functional property for reducing oxidative stress in sensitive skin.
  • Collagen Booster: High-purity TECA provides a significant functional property for anti-wrinkle efficacy.

6. Usage & Formulation Guide

Recommended Dosage: 0.1% – 1.0% (Standardized 10% powder); 0.1% – 0.5% (High-purity TECA).

pH Stability Matrix: Stable between pH 4.5 and 7.5. Best results achieved in slightly acidic to neutral emulsions.

Solubility: Our CWD Grade (Cold Water Dispersible) is designed for instant dissolution in aqueous serums. Standard TECA is soluble in ethanol and propylene glycol.

7. Industrial Evolution

The market has evolved from crude Gotu Kola juice to Purified Triterpene Isolate (TECA). Exbiol® represents the fourth generation of this evolution, utilizing Multi-column chromatography to remove plant chlorophyll and heavy metals, providing a white-to-off-white powder that does not discolor final cosmetic formulations.

8. COA & Quality Control Specifications

Table 8.1: Heavy Metals (ICP-MS)

Item Specification Method
Lead (Pb) < 0.5 ppm ICP-MS
Arsenic (As) < 0.5 ppm ICP-MS
Mercury (Hg) < 0.1 ppm ICP-MS

Table 8.2: Pesticide Residue Multi-Screen

Item Specification Method
Total Pesticides < 0.01 mg/kg GC-MS/MS
Aflatoxin B1 Negative HPLC-MS

Table 8.3: Microbiological Analysis

Item Specification Method
Total Plate Count < 1,000 cfu/g USP <61>
Yeast & Mold < 100 cfu/g USP <61>
Pathogenic Bacteria Negative USP <62>

9. Manufacturing Flow Description

Harvesting (Aerial Part) → Cold-Water Washing → Ethanol Extraction (70% v/v) → Centrifugal Filtration → Macroporous Resin Chromatography → Concentration → Decolorization → Spray Drying → Micronization (80 Mesh) → Vacuum Sealing.

10. Storage & Packaging

Bulk Packaging: 25kg card-board drum with double PE inner liners.

Storage Conditions: Store at <25°C, humidity <60%. Centella is highly hygroscopic; ensure airtight sealing after every use. Shelf life: 24 months.

11. MOQ, Sample & Global Shipping

  • MOQ: 1kg for R&D trials; 25kg for bulk industrial orders.
  • Samples: 10g-50g free sample for lab evaluation.
  • Logistics: Fast dispatch to EU/USA via Air Freight (DHL/FedEx) or Temperature-controlled Sea Freight.

12. Clinical Data & Scientific Research

In-vivo studies on TECA demonstrate a 30% increase in hydroxyproline levels in dermal tissue over 8 weeks, indicating functional property support for collagen architecture. Comparative studies show that Madecassoside specifically reduces post-procedure erythema significantly faster than standard panthenol-based creams.

13. Applicable Industries

Premium Skincare
Wound Care OEM
Health Supplements

14. B2B Application Scenarios

Exbiol® bulk supply is optimized for Contract Manufacturers (OEM/ODM) developing “Cica-creams,” transparent soothing gels, and post-sun recovery lotions requiring high-purity, low-ash actives.

15. Industry Market Scenarios

For brands targeting the Clean Beauty and Hypoallergenic markets, our Centella Extract provides the verified safety profile needed to pass dermatologist-testing and sensitivity audits in the EU and USA.

16. Supplier Comparison & Procurement Guide

Buyer Check: Ash Content & Color Stability.

Low-grade Centella extracts often have ash levels >10% and a dark brown color that discolors creams. Exbiol® ensures ash content <5% and a stable off-white color profile, reducing formulation risk for Tier-1 brands.

17. Technical FAQ for Bulk Buyers

Q: What is the difference between Gotu Kola Powder and TECA?
A: Powder is ground root; TECA is a concentrated, chromatographic isolate of the four functional triterpenes at 95% purity.

Q: Is your Centella Extract water-soluble?
A: We offer a specialized CWD (Cold Water Dispersible) grade specifically for transparent serums and beverages.

Q: Does it contain Madecassoside?
A: Yes, our TECA is standardized for high Madecassoside levels (approx 40% of the triterpene profile).

Q: What is the lead time for a 500kg order?
A: Standard lead time is 3 working days from our Shaanxi central hub.

Q: Is it non-GMO certified?
A: Yes, all our raw materials are non-GMO and cultivated without prohibited pesticides.

Q: Can I get a full COA before I purchase?
A: Absolutely. Contact our technical team for the latest pre-shipment COA.

18. References & Regulatory Sources

Centella Asiatica Manufacturer & QA

Manufactured by Exbiol® (Shaanxi Zhonghong Investment Technology Co., Ltd.), a GMP-certified manufacturer specializing in high-purity botanical extracts for dermaceuticals and health applications.

✔ 95% TECA HPLC Purity
✔ Specific Marker Compound Verification
✔ Zero-Contamination Extraction
✔ Bulk Inventory Global Dispatch

📧 sales@exbiol.com | 🌐 www.exbiol.com

🛡️GMP Certified
🔬HPLC Tested
🌍Global Shipping
📦MOQ: 1kg/25kg
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